Native mitral valve fungal endocarditis caused by Aspergillus fumigatus: A case report.

ABSTRACT:

Introduction

Aspergillus endocarditis is a rare fungal infection associated with a poor prognosis. Most cases of Aspergillus endocarditis involve prosthetic valves, with native valve involvement being rarely reported.

Case presentation

A 53-year-old asian female patient presented with fever, chills, dyspnea, generalized fatigue, and significant weight loss one month after undergoing left lower lobectomy for a pulmonary abscess. Echocardiogram showed a large mobile vegetation with a broad base on the anterior leaflet of the mitral valve, resembling atrial myxoma. Despite negative blood cultures, circulating DNA of Aspergillus fumigatus was detected by metagenome Next Generation Sequencing, prompting the initiation of empiric antifungal therapy with voriconazole. Emergency sur

SUBMITTER: Zang X 

PROVIDER: S-EPMC10758863 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature