Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study.

ABSTRACT:

Background

Bacterial colonization is an essential aspect of bronchiectasis. Although Haemophilus influenzae is a frequent colonizer in some regions, its clinical impacts are poorly understood. This study aimed to elucidate the impact of H. influenzae colonization in patients with bronchiectasis.

Methods

This retrospective study screened adult patients diagnosed with bronchiectasis at a tertiary referral center between April 1, 2003, and May 16, 2021, in South Korea. Propensity score matching was used to match patients with and without H. influenzae colonization. We assessed the severity of bronchiectasis as per the bronchiectasis severity index, the incidence of exacerbation, differences in lung function, and all-cause mortality.

Results

Out of the 4,453 patients with

SUBMITTER: Yang SH 

PROVIDER: S-EPMC10759404 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature