Association of time spent outdoors with the risk of Parkinson's disease: a prospective cohort study of 329,359 participants.

ABSTRACT:

Background

Studies on the association between time spent outdoors and the development of Parkinson's disease (PD) are lacking, and whether this relationship differs in different subgroups (age, sex) remains unclear.

Objective

We here examined the association between time spent outdoors and the incidence of PD in different seasons.

Methods

This study included 329,359 participants from the UK Biobank. Data regarding hours spent outdoors during a typical day were obtained through questionnaires. Cox proportional hazard regression models were used to estimate hazard ratios (HRs) for the association between exposure to outdoors duration and PD incidence. Restricted cubic spline was used to explore the potential nonlinear relationship between time spent outdoors and PD risk

SUBMITTER: Hu L 

PROVIDER: S-EPMC10759452 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature