Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium.

ABSTRACT:

Background

To assess repeatability and reproducibility of corneal epithelium thickness (ET) measured by a spectral-domain optical coherence tomographer (SD-OCT)/Placido topographer (MS-39, CSO, Florence, Italy) in keratoconus (KC) population at different stages, as well as to determine the progression limits for evaluating KC progression.

Methods

A total of 149 eyes were enrolled in this study, with 29 eyes in the forme fruste keratoconus (FFKC) group, 34 eyes in the mild KC group, 40 eyes in the moderate KC group, and 46 eyes in the severe KC group. Employing the within-subject standard deviation (S_w), test-retest variability (TRT), coefficient of variation (CoV), and intraclass correlation coefficient (ICC) to evaluate intraoperator repeatability and interoperat

SUBMITTER: Ning R 

PROVIDER: S-EPMC10759576 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature