Identification of eQTLs using different sets of single nucleotide polymorphisms associated with carcass and body composition traits in pigs.

ABSTRACT:

Background

Mapping expression quantitative trait loci (eQTLs) in skeletal muscle tissue in pigs is crucial for understanding the relationship between genetic variation and phenotypic expression of carcass traits in meat animals. Therefore, the primary objective of this study was to evaluate the impact of different sets of single nucleotide polymorphisms (SNP), including scenarios removing SNPs pruned for linkage disequilibrium (LD) and SNPs derived from SNP chip arrays and RNA-seq data from liver, brain, and skeletal muscle tissues, on the identification of eQTLs in the Longissimus lumborum tissue, associated with carcass and body composition traits in Large White pigs. The SNPs identified from muscle mRNA were combined with SNPs identified in the brain and liver tissue transcripto

SUBMITTER: Freitas FAO 

PROVIDER: S-EPMC10759680 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature