A cognitive map for value-guided choice in ventromedial prefrontal cortex.

ABSTRACT: The prefrontal cortex is crucial for economic decision-making and representing the value of options. However, how such representations facilitate flexible decisions remains unknown. We reframe economic decision-making in prefrontal cortex in line with representations of structure within the medial temporal lobe because such cognitive map representations are known to facilitate flexible behaviour. Specifically, we framed choice between different options as a navigation process in value space. Here we show that choices in a 2D value space defined by reward magnitude and probability were represented with a grid-like code, analogous to that found in spatial navigation. The grid-like code was present in ventromedial prefrontal cortex (vmPFC) local field potential theta frequency and the result

SUBMITTER: Veselic S 

PROVIDER: S-EPMC10760117 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature