The burden of influenza and the role of influenza vaccination in adults aged 50-64 years: A summary of available evidence.

ABSTRACT: Influenza is a vaccine-preventable disease and a global public health problem. Although most national influenza vaccination recommendations focus on subjects aged ≥65 years, an extensive burden of influenza has also been reported in those aged ≥50 years and is exacerbated by immune system aging. The main purpose of this review is to provide an overview of the burden of influenza and its potential prevention within the 50-64 age-group. These subjects account for a large proportion of the workforce, and play a central economic and social role. Individuals aged 50-64 years had a 3-times higher rate of hospitalization and a 9-fold higher mortality rate attributable to influenza than those aged 18-49-years, generating higher influenza-related hospitalization costs. Available data suggest that i

SUBMITTER: Marchi S 

PROVIDER: S-EPMC10760501 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature