Subclinical thyroid dysfunction and the risk of incident atrial fibrillation: A systematic review and meta-analysis.

ABSTRACT:

Background

Thyroid hormones act on the cardiovascular system directly by modulating its function and indirectly by transcriptional regulation of gene expression in the heart and the vasculature. Studies have shown associations between overt and subclinical thyroid disorders and cardiovascular outcomes. The aim of this study was to perform a systematic review and meta-analysis to assess the potential relationships between subclinical hyper- and hypothyroidism and risk of atrial fibrillation (AF), and post-operative AF.

Methods

MEDLINE and Scopus databases were searched from inception to 18th February 2023 for randomised controlled trials, case-control studies, and cohort studies which assessed the relationship between subclinical thyroid dysfunction and incident AF events. Ri

SUBMITTER: Singh H 

PROVIDER: S-EPMC10760776 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature