History of exposure to copper influences transgenerational gene expression responses in Daphnia magna.

ABSTRACT: The establishment of transgenerational effects following chemical exposure is a powerful phenomenon, capable of modulating ecosystem health beyond exposure periods. This study assessed the transgenerational effects occurring due to copper exposure in the invertebrate D. magna at the transcriptional level, while evaluating the role of exposure history on such responses. Thus, daphnids acclimated for several generations in a copper vs. clean medium were then exposed for one generation (F0) to this metal, and monitored for the following non-exposed generations (F1, F2 and F3). Organisms differing in exposure histories showed remarkably different transcriptional profiles at the F0, with naïve organisms being more profoundly affected. These trends were confirmed for F3 treatments, which

SUBMITTER: Jeremias G 

PROVIDER: S-EPMC10761054 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature