Changes in Early T-Cell Subsets and Their Impact on Prognosis in Patients with Sepsis: A Single-Center Retrospective Study.

ABSTRACT:

Objective

To analyze the early changes in CD3⁺, CD4⁺, and CD8⁺T-cell subset counts in patients with sepsis and their correlation with prognosis to provide a feasible basis for clinical immunomodulation in sepsis.

Methods

This is a single-center retrospective study. The study enrolled sepsis patients (meeting SEPSIS 3.0 definition) who were admitted to the Department of Intensive Care Unit at the First Hospital of Jilin University from July 5th, 2018 to December 5th, 2019 and were aged 18 years or above. In addition, these patients underwent cellular immune testing (CD3⁺, CD4⁺, CD8⁺ T lymphocyte counts, and CD4⁺/CD8⁺ ratio) within 24 hours of ICU admission. Patient's clinical data includin

SUBMITTER: Li Y 

PROVIDER: S-EPMC10761232 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature