Patients with episodic migraine without aura have an increased rate of delayed discounting.

ABSTRACT:

Objective

This study aimed to explore decision-making impulsivity and its neural mechanisms in patients with episodic migraine without aura (EMoA).

Background

Previous evidence indicates increased impulsivity and altered reward processing in patients with chronic migraine and medication overuse; however, whether the same holds true for those with EMoA is unclear.

Methods

Patients newly diagnosed with EMoA (n = 51) and healthy controls (HC, n = 45) were recruited. All participants completed delay discounting task, cognitive assessments, a questionnaire for headache profile, and resting-state function magnetic resonance imaging scans. Resting-state functional connectivity (RSFC) between the regions of interest and the entire brain was explored.

Results

Patients w

SUBMITTER: Wang L 

PROVIDER: S-EPMC10761331 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature