The association between anterior cruciate ligament degeneration and incident knee osteoarthritis: Data from the osteoarthritis initiative.

ABSTRACT:

Background

Though anterior cruciate ligament (ACL) tear has been widely accepted as an important accelerator for knee osteoarthritis (KOA), the role of intrinsic ACL degeneration in developing KOA has not been fully investigated.

Purpose

To determine whether ACL degeneration, in the absence of ACL tear, is associated with incident KOA over 4 years.

Study design

Cohort study; Level of evidence, 2.

Methods

Participants' knees in this nested case-control study were selected from the Osteoarthritis Initiative (OAI) study, with Kellgren-Lawrence grading (Kellgren-Lawrence grading) of 0 or 1 ​at baseline (BL). Case knees which had incident KOA (KLG ≥2) over 4 years, were matched 1:1 with control knees by gender, age and radiographic status. ACL signal intensity alter

SUBMITTER: Luo P 

PROVIDER: S-EPMC10762318 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature