Association of serum 25-hydroxyvitamin D levels with aggressiveness of papillary thyroid cancer.

ABSTRACT:

Objective

Serum 25-hydroxyvitamin D (25(OH)D) deficiency has been known to be associated with the risk and mortality of several cancers. However, the role of 25(OH)D in papillary thyroid cancer (PTC) remains controversial. This study aimed to investigate the association between 25(OH)D and clinicopathologic features of PTC.

Methods

Patients who underwent thyroidectomy were retrospectively reviewed. Serum 25(OH)D levels were measured within a week prior to surgery. The patients were categorized into four quartiles according to season-specific 25(OH)D levels. The association between 25(OH)D levels and clinicopathologic features of PTC was analyzed.

Results

A total of 2932 patients were enrolled in the study. The 25(OH)D levels were significantly higher in patients with

SUBMITTER: Shao Y 

PROVIDER: S-EPMC10762552 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature