Interpregnancy interval and early infant neurodevelopment: the role of maternal-fetal glucose metabolism.

ABSTRACT:

Background

Interpregnancy interval (IPI) is associated with a variety of adverse maternal and infant outcomes. However, reports of its associations with early infant neurodevelopment are limited and the mechanisms of this association have not been elucidated. Maternal-fetal glucose metabolism has been shown to be associated with infant neurodevelopmental. The objective of this study was to determine whether this metabolism plays a role in the relationship between IPI and neurodevelopment.

Methods

This prospective birth cohort study included 2599 mother-infant pairs. The IPI was calculated by subtracting the gestational age of the current pregnancy from the interval at the end of the previous pregnancy. Neurodevelopmental outcomes at 12 months in infants were assessed by the

SUBMITTER: Ma R 

PROVIDER: S-EPMC10762827 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature