Effects of altitude on thyroid disorders according to Chinese three-rung, ladder-like topography: national cross-sectional study.

ABSTRACT:

Background

Chinese topography appears a three-rung ladder-like distribution of decreasing elevation from northwest to southeast, which is divided by two sloping edges. Previous studies have reported that prevalence of thyroid diseases differed by altitude, and geographical factors were associated with thyroid disorders. To explore the association between three-rung ladder-like regions and thyroid disorders according to unique Chinese topographic features, we conducted an epidemiological cross-sectional study from 2015-2017 that covered all 31 mainland Chinese provinces.

Methods

A total of 78,470 participants aged ≥ 18 years from a nationally representative cross-sectional study were included. Serum thyroid peroxidase antibody, thyroglobulin antibody, and thyroid-stimulating

SUBMITTER: Gong B 

PROVIDER: S-EPMC10762831 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature