Optimization of bacterioruberin production from Halorubrum ruber and assessment of its antioxidant potential.

ABSTRACT: Haloarchaea produce bacterioruberin, a major C₅₀ carotenoid with antioxidant properties that allow for its potential application in the food, cosmetic, and pharmaceutical industries. This study aimed to optimize culture conditions for total carotenoid, predominantly comprising bacterioruberin, production using Halorubrum ruber MBLA0099. A one-factor-at-a-time and statistically-based experimental design were applied to optimize the culture conditions. Culture in the optimized medium caused an increase in total carotenoid production from 0.496 to 1.966 mg L^- 1 Maximal carotenoid productivity was achieved in a 7-L laboratory-scale fermentation and represented a 6.05-fold increase (0.492 mg L^-1 d^-1). The carotenoid extracts from strain MBLA0099 exhib

SUBMITTER: Hwang CY 

PROVIDER: S-EPMC10762969 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature