Analysis of fecal microbiome and metabolome changes in goats with pregnant toxemia.

ABSTRACT:

Background

Pregnancy toxemia is a common disease, which occurs in older does that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of goat breeding enterprises. The disease is believed to be caused by malnutrition, stress, and other factors, that lead to the disorder of lipid metabolism, resulting in increased ketone content, ketosis, ketonuria, and neurological symptoms. However, the changes in gut microbes and their metabolism in this disease are still unclear. The objective of this experiment was to evaluate the effect of toxemia of pregnancy on the fecal microbiome and metabolomics of does.

Results

Eight pregnant does suspected of having toxemia of pregnancy (PT group)

SUBMITTER: Jin B 

PROVIDER: S-EPMC10763682 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature