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The treatment efficacy of radiotherapy for optic nerve sheath meningioma.


ABSTRACT:

Objectives

Optic nerve sheath meningioma (ONSM) is a rare benign tumour that accounts for approximately 2% of all orbital tumours. Radiotherapy has gradually become an important treatment for ONSM because of its good effect in preserving or improving vision. We aimed to explore the effect of radiotherapy on tumour control and vision preservation/improvement in patients with ONSM.

Methods

Forty-three patients with primary ONSM treated in our institution from 2015 to 2021 were enrolled. The irradiation dose was from 50.4 to 54 Gy with 28-30 fractions. We evaluated the tumour volume on MRI or CT, and visual acuity before and after the radiotherapy.

Results

Thirty-four patients (79%) experienced a vision decrease at diagnosis. The mean duration of follow-up was 54.1 month

SUBMITTER: Tang T 

PROVIDER: S-EPMC10764342 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature