Fatigue and quality of life during neoadjuvant chemotherapy of early breast cancer: a prospective multicenter cohort study.

ABSTRACT:

Background

Few measurements of fatigue and quality of life have been performed during neoadjuvant chemotherapy of early breast cancer. This study evaluates fatigue and quality of life experienced by early breast cancer patients during neoadjuvant chemotherapy and their association with different clinical parameters.

Methods

Fifty-four stage I-III patients' responses to the Multidimensional Fatigue Inventory (MFI) and to the Functional Assessment of Cancer Therapy-Breast (FACT-B) were analyzed by a linear covariance pattern model. Chemotherapy regimen, age, baseline fatigue level, body-mass-index and cancer stage were added to the model to estimate their impact on both outcomes.

Results

All fatigue dimensions worsened in clinically relevant levels. Physical fatigue wor

SUBMITTER: Pelzer F 

PROVIDER: S-EPMC10764505 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature