Exploring the potential of stratum corneum biomarkers for assessing psychological distress in health care workers: An observational pilot study.

ABSTRACT:

Backgrounds

The detection of biomarkers of a stress response in the stratum corneum (SC) could be used as objective assessment of early stress symptoms and monitoring of stress reduction interventions in health care workers (HCWs).

Aim

The aim of this study is to explore SC biomarkers of immune and hormonal response and skin barrier for assessment of psychological distress (PD) in HCWs.

Methods

Twenty-five female HCWs and 25 non-HCWs participated. SC samples were collected using adhesive tapes at baseline and 3-5 days later (T1). We analyzed 24 biomarkers (immunological, vascular, hormones, and natural moisturizing factors). Stress symptoms were assessed using three scales of Copenhagen Psychosocial Questionnaire. The study involved: identifying SC biomarkers, correla

SUBMITTER: Emal LM 

PROVIDER: S-EPMC10764658 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature