Impaired vision in children prenatally exposed to methadone: an observational cohort study.

ABSTRACT:

Background/objectives

To examine prevalence of failed visual assessment at 8-10 years in children born to methadone-maintained opioid dependent (MMOD) mothers and relate this to known in utero substance exposure.

Subjects/methods

Follow up of observational cohort study of methadone-exposed and comparison children matched for birthweight, gestation and postcode of residence at birth. Participants were 144 children (98 exposed, 46 comparison). Prenatal drug exposure was previously established via comprehensive maternal and neonatal toxicology. Children were invited to attend for visual assessment and casenotes were reviewed. Presence of acuity poorer than 0.2 logMAR, strabismus, nystagmus and/or impaired stereovision constituted a 'fail'. Fail rates were compared between metha

SUBMITTER: Hamilton R 

PROVIDER: S-EPMC10764882 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature