Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea.

ABSTRACT:

Backgruound

Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly.

Methods

We used the Korean nationwide claims database from 2009 to 2019. A total of 931 patients with acromegaly who had never used an osteoporosis drug before and were treated with surgery alone were selected as study participants, and a 1:29 ratio of 26,999 age- and sex-matched osteoporosis drug-naïve controls without acromegaly were randomly selected from the database.

Results

The mean age was 46.2 years, and 50.0% were male. During a median follow-up of 54.1 months, there was no difference in the risks of all, vertebral, and non

SUBMITTER: Kim J 

PROVIDER: S-EPMC10764994 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature