An insight into genes responsible for fosfomycin resistance among uropathogens of asymptomatic bacteriuria during pregnancy: A North Indian study.

ABSTRACT:

Purpose

Asymptomatic bacteriuria (ASB) is a common finding during pregnancy. Effective antibiotic treatment could reduce its adverse effects on both mother and fetus. However, emerging antimicrobial resistance limits the treatment options. Fosfomycin might be a promising drug in this regard, as its resistance is still low. The aim of the study was to determine the antimicrobial susceptibility pattern of fosfomycin in isolates causing ASB by disc diffusion and agar dilution (in selected isolates), determine minimum inhibitory contribution (MIC) by agar dilution in isolates resistant by disc diffusion and detect the genes responsible for fosfomycin resistance.

Methods

This was a 2-year study carried in the Department of Microbiology, Jawaharlal Nehru Medical College and Hospit

SUBMITTER: Khatoon S 

PROVIDER: S-EPMC10765046 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature