Postural fall in systolic blood pressure is a useful warning sign in dengue fever.

ABSTRACT:

Background

Capillary leak is the hallmark of development of severe dengue. A rise in haematocrit has been a major warning sign in WHO guidelines. Postural hypotension, which could reflect the intravascular volume reduction in capillary leak has been noted as warning sign in CDC and Pan American Health Organisation guidelines. We evaluated the diagnostic accuracy of postural hypotension as a marker of development of severe dengue.

Methods

150 patients admitted with dengue fever were recruited in this prospective observational study. Diagnostic accuracy of conventional warning signs (abdominal pain, persistent vomiting, fluid accumulation, mucosal bleeding, lethargy, liver enlargement, increasing hematocrit with decreasing platelets) and postural hypotension was evaluated.

SUBMITTER: Mahabala C 

PROVIDER: S-EPMC10765096 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature