Maternal Prenatal Infections and Biliary Atresia in Offspring.

ABSTRACT:

Importance

Investigations into the association of antepartum maternal infections with the pathogenesis of biliary atresia (BA) in human offspring are insufficient.

Objective

To examine the association between prenatal infections in mothers and the development of BA in their offspring.

Design, setting, and participants

This population-based case-control study obtained administrative data from the Taiwan National Health Insurance Research Database with linkage to the Taiwan Maternal and Child Health Database, capturing demographic and medical information on nearly all 23 million of the Taiwan population. The cohort comprised 2 905 978 singleton live births among mother-infant dyads between January 1, 2004, and December 31, 2020, in Taiwan. The case group of infants with

SUBMITTER: Wang WH 

PROVIDER: S-EPMC10765264 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature