Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index is regarded as a sophisticated surrogate biomarker for insulin resistance, offering a refined means for evaluating cardiovascular diseases (CVDs). However, prospective cohort studies have not simultaneously conducted baseline and multi-timepoint trajectory assessments of the TyG index in relation to CVDs and their subtypes in elderly participants.

Methods

After excluding data deficiencies and conditions that could influence the research outcomes, this study ultimately incorporated a cohort of 20,185 participants, with data chronicles extending from 2016 to 2022. The TyG index was calculated as Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)/2]. Latent Class Trajectory Model (LCTM) was used to assess the change trends

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10765625 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature