Oscillometry for personalizing continuous distending pressure maneuvers: an observational study in extremely preterm infants.

ABSTRACT:

Rationale

Lung recruitment and continuous distending pressure (CDP) titration are critical for assuring the efficacy of high-frequency ventilation (HFOV) in preterm infants. The limitation of oxygenation (peripheral oxygen saturation, SpO₂) in optimizing CDP calls for evaluating other non-invasive bedside measurements. Respiratory reactance (Xrs) at 10 Hz measured by oscillometry reflects lung volume recruitment and tissue strain. In particular, lung volume recruitment and decreased tissue strain result in increased Xrs values.

Objectives

In extremely preterm infants treated with HFOV as first intention, we aimed to measure the relationship between CDP and Xrs during SpO₂-driven CDP optimization.

Methods

In this prospective observational study, e

SUBMITTER: Veneroni C 

PROVIDER: S-EPMC10765834 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature