Physiological roles of propolis and red ginseng nanoplatforms in alleviating dexamethasone-induced male reproductive challenges in a rat model.

ABSTRACT:

Background

Red ginseng and propolis are well-known antioxidants that have been related to a reduction in oxidative stress.

Objective

This study evaluated the efficiency of red ginseng and propolis, either in powder or as nano-forms against dexamethasone-induced testicular oxidative challenges in adult male albino rats.

Methods

Forty rats were divided into 8 equal groups including control negative group that was given vehicle (DMSO), control positive group that was administered dexamethasone in addition to the nano-propolis, nano-ginseng, nano-propolis + dexamethasone, nano ginseng+dexamethasone, propolis+dexamethasone and ginseng + dexamethasone groups. Serum, semen and tissue samples were obtained.

Results

Lower testosterone levels, higher levels of MDA, and l

SUBMITTER: Aziz RLA 

PROVIDER: S-EPMC10766727 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature