Postural orthostatic tachycardia syndrome after COVID-19 vaccination.

ABSTRACT:

Background

There is an association between coronavirus disease 2019 (COVID-19) mRNA vaccination and the incidence or exacerbation of postural orthostatic tachycardia syndrome (POTS).

Objective

The purpose of this study was to characterize patients reporting new or exacerbated POTS after receiving the mRNA COVID-19 vaccine.

Methods

We prospectively collected data from sequential patients in a POTS clinic between July 2021 and June 2022 reporting new or exacerbated POTS symptoms after COVID-19 vaccination. Heart rate variability (HRV) and skin sympathetic nerve activity (SKNA) were compared against those of 24 healthy controls.

Results

Ten patients (6 women and 4 men; age 41.5 ± 7.9 years) met inclusion criteria. Four patients had standing norepinephrine levels >

SUBMITTER: Teodorescu DL 

PROVIDER: S-EPMC10767226 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature