Temporal patterns of pre- and post-natal target organ damage associated with hypertensive pregnancy: a systematic review.

ABSTRACT:

Aims

Hypertensive pregnancy is associated with increased risks of developing a range of vascular disorders in later life. Understanding when hypertensive target organ damage first emerges could guide optimal timing of preventive interventions. This review identifies evidence of hypertensive target organ damage across cardiac, vascular, cerebral, and renal systems at different time points from pregnancy to postpartum.

Methods and results

Systematic review of Ovid/MEDLINE, EMBASE, and ClinicalTrials.gov up to and including February 2023 including review of reference lists. Identified articles underwent evaluation via a synthesis without meta-analysis using a vote-counting approach based on direction of effect, regardless of statistical significance. Risk of bias was assessed f

SUBMITTER: Cutler HR 

PROVIDER: S-EPMC10767256 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature