Association of HIV infection and cognitive impairment in older adults: A meta-analysis.

ABSTRACT:

Objective

To synthesize evidence on the association between human immunodeficiency virus (HIV) infection and cognitive impairment in older adults.

Design

Meta-analysis.

Participants

Adults aged 50 years or older.

Methods

In this systematic literature review and meta-analysis, we searched PubMed, Scopus, Embase, and APA/PsycNet for studies published before July 21, 2020, that assessed the association between HIV-infection and cognitive impairment. We calculated pooled odds ratios (ORs) of cognitive impairment for people living with HIV (PLWH) and 95 % confidence intervals (CIs) using random-effect models and calculated pooled mean difference (MD) for major cognitive domains between PLWH and HIV-uninfected adults. We assessed risk of bias using the Newcastle-Otta

SUBMITTER: Deng L 

PROVIDER: S-EPMC10767715 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature