Maternal self-reported polycystic ovary syndrome with offspring and maternal cardiometabolic outcomes.

ABSTRACT:

Study question

Do children born to mothers with polycystic ovary syndrome (PCOS) have an adverse cardiometabolic profile including arterial stiffness at 9 years of age compared to other children?

Summary answer

Children of mothers with PCOS did not have differing cardiometabolic outcomes than children without exposure.

What is known already

While women with PCOS themselves have higher risk of cardiometabolic conditions such as obesity and diabetes, the evidence on intergenerational impact is unclear. Given in utero sequalae of PCOS (e.g. hyperandrogenism, insulin resistance), the increased risk could be to both boys and girls.

Study design, size, duration

The Upstate KIDS cohort is a population-based birth cohort established in 2008-2010 to prospectively study

SUBMITTER: Polinski KJ 

PROVIDER: S-EPMC10767861 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature