M7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome.

ABSTRACT: With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of thousands of experimentally validated m7G sites have been discovered in various species, shedding light on the significant role of m7G modification in regulating numerous biological processes including disease pathogenesis. An integrated resource that enables the sharing, annotation and customized analysis of m7G data will greatly facilitate m7G studies under various physiological contexts. We previously developed the m7GHub database to host mRNA m7G sites identified in the human transcriptome. Here, we present m7GHub v.2.0, an updated resource for a comprehensive collection of m7G modifications in various types of RNA across multiple species: an m7GDB database containing 430 898 putative m7G sites iden

SUBMITTER: Wang X 

PROVIDER: S-EPMC10767970 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature