DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms.

ABSTRACT: The Drug-Gene Interaction Database (DGIdb, https://dgidb.org) is a publicly accessible resource that aggregates genes or gene products, drugs and drug-gene interaction records to drive hypothesis generation and discovery for clinicians and researchers. DGIdb 5.0 is the latest release and includes substantial architectural and functional updates to support integration into clinical and drug discovery pipelines. The DGIdb service architecture has been split into separate client and server applications, enabling consistent data access for users of both the application programming interface (API) and web interface. The new interface was developed in ReactJS, and includes dynamic visualizations and consistency in the display of user interface elements. A GraphQL API has been added to support cu

SUBMITTER: Cannon M 

PROVIDER: S-EPMC10767982 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature