Cortical gray-white matter contrast abnormalities in male children with attention deficit hyperactivity disorder.

ABSTRACT:

Purpose

Presently, research concerning alterations in brain structure among individuals with attention deficit hyperactivity disorder (ADHD) predominantly focuses on entire brain volume and cortical thickness. In this study, we extend our examination to the cortical microstructure of male children with ADHD. To achieve this, we employ the gray-white matter tissue contrast (GWC) metric, allowing for an assessment of modifications in gray matter density and white matter microstructure. Furthermore, we explore the potential connection between GWC and the severity of disorder in male children by ADHD.

Methods

We acquired 3DT1 sequences from the public ADHD-200 database. In this study, we conducted a comparative analysis between 43 male children diagnosed with ADHD and 50 age-mat

SUBMITTER: Wang C 

PROVIDER: S-EPMC10768013 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature