Changes in the urinary proteome of rats after short-term intake of magnesium L-threonate(MgT).

ABSTRACT:

Introduction

Magnesium (Mg) is an important mineral in living organisms. Magnesium has multiple functions in the human body, wherein it plays an important therapeutic and preventive role in a variety of diseases.

Methods

Urine samples of rats before and after gavage of magnesium L-threonate (MgT) were collected, and the urinary proteome was identified using the LC-MS/MS technique and analyzed using various databases.

Results and discussion

The results illustrated that the urinary proteome of rats was significantly altered after short-term intake of magnesium supplements and that the differential proteins and the biological functions were related to magnesium. This study innovatively establishes a method to study nutrients from the perspective of urine proteomics. This

SUBMITTER: Shen Z 

PROVIDER: S-EPMC10768015 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature