Identification of neural circuits controlling male sexual behavior and sexual motivation by manganese-enhanced magnetic resonance imaging.

ABSTRACT:

Introduction

Different techniques have been used to identify the brain regions that control sexual motivation and sexual behavior. However, the influence of sexual experience on the activation of these brain regions in the same subject is unknown. Using manganese-enhanced magnetic resonance imaging (MEMRI), we analyzed the activation of brain regions in the sexual incentive motivation (SIM) and the partner preference PP (tests) on weeks 1, 5, and 10 in male rats tested for 10 weeks. AIM. In experiment 1, we analyzed the possible toxic effects of 16 mg/kg of MnCl₂ on male sexual behavior, running wheel, and motor execution. In experiment 2, subjects were tested for SIM and PP using MEMRI.

Methods

In both experiments, a dose of 16 mg/kg (s.c) of chloride manganese (

SUBMITTER: Gaytan-Tocaven L 

PROVIDER: S-EPMC10768062 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature