Brothers with Becker muscular dystrophy show discordance in skeletal muscle computed tomography findings: A case report.

ABSTRACT: Becker muscular dystrophy is caused by DMD mutations and is characterized by progressive muscle atrophy. The wide variations observed in muscle atrophy progression in Becker muscular dystrophy are considered multifactorial, including differences in mutations and environmental factors. In this case, two brothers, aged 2 and 3 years, had the identical DMD mutation, confirming their Becker muscular dystrophy diagnosis. They began using handrails when ascending and descending stairs at the age of 16 due to progressive muscular weakness. Over an 18-year follow-up, the older brother consistently had high serum creatine kinase levels, significantly over median levels. Muscle computed tomography finings revealed that the older brother's gluteus maximus and vastus femoris cross-sectio

SUBMITTER: Nambu Y 

PROVIDER: S-EPMC10768573 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature