Blood pressure reduction after renal denervation in patients with or without chronic kidney disease.

ABSTRACT:

Background

Renal denervation (RDN) has emerged as an adjacent option for the treatment of hypertension. This analysis of the Erlanger registry aimed to compare the blood pressure (BP)-lowering effects and safety of RDN in patients with and without chronic kidney disease (CKD).

Methods

In this single-center retrospective analysis, 47 patients with and 127 without CKD underwent radiofrequency-, ultrasound- or alcohol-infusion-based RDN. Office and 24-h ambulatory BP and estimated glomerular filtration rate (eGFR) were measured at baseline, and after 6 and 12 months.

Results

A total of 174 patients with a mean age of 59.0 ± 10 years were followed up for 12 months. At baseline, mean eGFR was 55.8 ± 21 mL/min/1.73 m² in patients with CKD and 87.3 ± 13 mL/min/1.7

SUBMITTER: Gunes-Altan M 

PROVIDER: S-EPMC10768756 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature