Gender-specific risk factors and outcomes of hyperkalemia in CKD patients: smoking as a driver of hyperkalemia in men.

ABSTRACT:

Background

Hyperkalemia is common among patients with chronic kidney disease (CKD) but there is scarce information on differential risk factors and outcomes for men and women. For instance, smoking has been suggested to be a risk factor for hyperkalemia, but specific analysis of the sex-specific impact of smoking on hyperkalemia in CKD is lacking.

Methods

We studied serum potassium levels in 2891 participants from the NEFRONA cohort: 483 controls (47% women) and 2408 CKD patients (38% women) without prior cardiovascular disease (CVD), assessing whether smoking is a risk factor for hyperkalemia, and if hyperkalemia is associated with outcomes separately for men and women.

Results

Median potassium levels and prevalence of hypo and hyperkalemia were higher in CKD partici

SUBMITTER: Valdivielso JM 

PROVIDER: S-EPMC10768768 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature