Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies.

ABSTRACT:

Objectives

To systematically analyze available prospective evidence on the association between HIV infection and incident heart failure (HF).

Methods

A systematic search of PubMed, EMBASE, Web of Science, and manual search of relevant articles through June 1st, 2020, was conducted. Two authors independently performed full-text assessments and data extraction. The pooled relative risk with 95% confidence interval was estimated using DerSimonian and Laird random-effects models, with inverse-variance fixed-effects meta-analysis used as a sensitivity analysis. Heterogeneity was explored using subgroup analyses and meta-regressions.

Results

We included 8 reports among 8,848,569 participants with 101,335 incident cases of HF [1941 among 131,632 people living with HIV (PLWH)

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10768809 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature