Therapeutic value of lymph node dissection for Siewert type II and III adenocarcinoma: meta-analysis.

ABSTRACT:

Background

Adenocarcinoma of the oesophagogastric junction presents an increasing incidence. Surgical resection with lymphadenectomy is the only curative treatment modality at the present time, but the optimal extent of lymphadenectomy is debatable. The aim of the present meta-analysis was to estimate the therapeutic value of each nodal station.

Methods

Studies reporting the therapeutic value index of each nodal station in Siewert types II/III oesophagogastric junction (EGJ) were searched in PubMed, Web of Science and Embase up to October 2022. This index was calculated by multiplication of metastatic incidence and 5-year overall survival rate at each nodal station. Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Prevalence Studie

SUBMITTER: Chen XD 

PROVIDER: S-EPMC10768987 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature