Impact of systemic antimicrobial therapy on the faecal microbiome in symptomatic dairy cows.

ABSTRACT: Antimicrobial resistance is a global threat to human and animal health, with the misuse and overuse of antimicrobials suggested as the main drivers of resistance. Antimicrobial therapy can alter the bacterial community composition and the faecal resistome in cattle. Little is known about the impact of systemic antimicrobial therapy on the faecal microbiome in dairy cows in the presence of disease. Therefore, this study aimed to assess the impact of systemic antimicrobial therapy on the faecal microbiome in dairy cows in the pastoral farm environment, by analysing faecal samples from cattle impacted by several different clinically-defined conditions and corresponding antimicrobial treatments. Analysis at the individual animal level showed a decrease in bacterial diversity and richness durin

SUBMITTER: Collis RM 

PROVIDER: S-EPMC10769045 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature