Specialization of the Human Hippocampal Long Axis Revisited.

ABSTRACT: The hippocampus possesses anatomical differences along its long axis. Here the functional specialization of the human hippocampal long axis was explored using network-anchored precision functional MRI (N = 11) paired with behavioral analyses (N=266). Functional connectivity analyses demonstrated that the anterior hippocampus was preferentially correlated with a cerebral network associated with remembering, while the posterior hippocampus was correlated with a distinct network associated with behavioral salience. Seed regions placed within the hippocampus recapitulated the distinct cerebral networks. Functional characterization using task data within the same intensively sampled individuals discovered a functional double dissociation between the anterior and posterior hippocampal regions. T

SUBMITTER: Angeli PA 

PROVIDER: S-EPMC10769203 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature