Reduced Lateralization of Multiple Functional Brain Networks in Autistic Males.

ABSTRACT:

Background

Autism spectrum disorder has been linked to a variety of organizational and developmental deviations in the brain. One such organizational difference involves hemispheric lateralization, which may be localized to language-relevant regions of the brain or distributed more broadly.

Methods

In the present study, we estimated brain hemispheric lateralization in autism based on each participant's unique functional neuroanatomy rather than relying on group-averaged data. Additionally, we explored potential relationships between the lateralization of the language network and behavioral phenotypes including verbal ability, language delay, and autism symptom severity. We hypothesized that differences in hemispheric asymmetries in autism would be limited to the language net

SUBMITTER: Peterson M 

PROVIDER: S-EPMC10769214 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature