Persistent enrichment of multidrug resistant Klebsiella in oral and nasal communities during long-term starvation.

ABSTRACT: The human oral and nasal cavities can act as reservoirs for opportunistic pathogens capable of causing acute infection. These microbes asymptomatically colonize the human oral and nasal cavities which facilitates transmission within human populations via the environment, and they routinely possess a clinically-significant antibiotic-resistance genes. Among these opportunistic pathogens, the Klebsiella genus stands out as a notable example, with its members frequently linked to nosocomial infections and multidrug resistance. As with many colonizing opportunistic pathogens, how Klebsiella transitions from an asymptomatic colonizer to a pathogen remains unclear. Here, we explored a possible explanation by investigating the ability of oral and nasal Klebsiella to outcompet

SUBMITTER: Liu J 

PROVIDER: S-EPMC10769290 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature