Linked <i>OXTR</i> Variants Are Associated With Social Behavior Differences in Bonobos (<i>Pan paniscus</i>).

ABSTRACT: Single-nucleotide polymorphisms (SNPs) in forkhead box protein P2 (FOXP2), oxytocin receptor (OXTR), and arginine vasopressin receptor gene 1A (AVPR1A) have been associated with linguistic and social development in humans, as well as symptom severity in autism. Studying biobehavioral mechanisms in the species most closely related to humans can provide insights into the origins of human communication, and the impact of genetic variation on complex behavioral phenotypes. Here, we tested the hypothesis that similar genetic factors underlie social communication differences in both bonobos (Pan paniscus) and humans. We analyzed Sanger sequencing results to determine if bonobos exhibit individual variation at 10 loci across FOXP2, OXTR, and AVPR1A

SUBMITTER: Skiba SA 

PROVIDER: S-EPMC10769379 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature