Genome-Wide Network Analysis of Above- and Below-Ground Co-growth in Populus euphratica.
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ABSTRACT: Tree growth is the consequence of developmental interactions between above- and below-ground compartments. However, a comprehensive view of the genetic architecture of growth as a cohesive whole is poorly understood. We propose a systems biology approach for mapping growth trajectories in genome-wide association studies viewing growth as a complex (phenotypic) system in which above- and below-ground components (or traits) interact with each other to mediate systems behavior. We further assume that trait-trait interactions are controlled by a genetic system composed of many different interactive genes and integrate the Lotka-Volterra predator-prey model to dissect phenotypic and genetic systems into pleiotropic and epistatic interaction components by which the detailed genetic mechanism of
SUBMITTER: Lu K
PROVIDER: S-EPMC10769449 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
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