The relationship between disease-specific psychosocial stressors and depressive symptoms in Huntington's disease.

ABSTRACT:

Background

Huntington's disease (HD) is an inherited neurodegenerative disease involving motor abnormalities, cognitive decline, and psychological difficulties. Depression is among the most common psychological difficulties in HD. People with HD encounter numerous stressors related to their diagnosis and the impact of HD on their daily lives. Understanding the relationship between HD-specific psychosocial stressors and depression symptoms is critical for optimising treatment and developing a holistic, disease-specific model of depression in HD.

Methods

Fifty-seven adults with the HD gene expansion (33 pre-symptomatic, 24 symptomatic) completed a self-report depression questionnaire and rated how much stress they experienced in relation to 20 psychosocial challenges commonly

SUBMITTER: Bilal H 

PROVIDER: S-EPMC10769991 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature