Bedside personalized methods based on electrical impedance tomography or respiratory mechanics to set PEEP in ARDS and recruitment-to-inflation ratio: a physiologic study.

ABSTRACT:

Background

Various Positive End-Expiratory Pressure (PEEP) titration strategies have been proposed to optimize ventilation in patients with acute respiratory distress syndrome (ARDS). We aimed to compare PEEP titration strategies based on electrical impedance tomography (EIT) to methods derived from respiratory system mechanics with or without esophageal pressure measurements, in terms of PEEP levels and association with recruitability.

Methods

Nineteen patients with ARDS were enrolled. Recruitability was assessed by the estimated Recruitment-to-Inflation ratio (R/I_est) between PEEP 15 and 5 cmH₂O. Then, a decremental PEEP trial from PEEP 20 to 5 cmH₂O was performed. PEEP levels determined by the following strategies were studied: (1) plateau

SUBMITTER: Pavlovsky B 

PROVIDER: S-EPMC10769993 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature